Boc-O-Tert-Butyl-L-Serine Dicyclohexylamine Salt
99% (N)
Reagent
Code: #66139
Alias
BOC-O-tert-butyl-L-serine dicyclohexylammonium salt; Boc-Ser(tBu)-OH dicyclohexylammonium salt
CAS Number
18942-50-2
science Other reagents with same CAS 18942-50-2
blur_circular Chemical Specifications
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Molecular Information
Weight
442.630 g/mol
Formula
C₂₄H₄₆N₂O₅
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Registry Numbers
MDL Number
MFCD00065590
thermostat
Physical Properties
Melting Point
161-164°C
Boiling Point
571.1ºC at 760 mmHg
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Storage & Handling
Storage
2-8°C, sealed, dry
description Product Description
This compound is primarily utilized in peptide synthesis as a protecting group for the hydroxyl and amino functionalities of serine. The Boc (tert-butoxycarbonyl) group safeguards the amino group, while the tert-butyl moiety protects the hydroxyl group, ensuring selective reactions during peptide chain assembly. The dicyclohexylamine salt form enhances the compound's stability and solubility, making it easier to handle in organic synthesis. It is particularly valuable in solid-phase peptide synthesis (SPPS) and other applications where precise control over amino acid reactivity is required. Its use enables the construction of complex peptides with high purity and efficiency.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Appearance | Solid |
| Purity | 98.5-100 |
| Specific rotation [α]_D^{20} (c=1) in DMF | 23-26 |
| Infrared Spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
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