Boc-D-Pen(Acm)-OH is a protected derivative of D-penicillamine, primarily used in peptide synthesis. The Boc (tert-butoxycarbonyl) group protects the N-terminus, while the Acm (acetamidomethyl) group protects the thiol side chain, enabling selective deprotection and incorporation into peptide chains without unwanted side reactions. It serves as a key building block in the production of complex peptides, particularly those requiring specific stereochemistry or disulfide bond formation strategies. Its applications are crucial in pharmaceutical development for synthesizing therapeutic peptides and in biochemical research to investigate peptide structures, interactions, and functions. The compound's stability and compatibility with standard protocols, such as Fmoc/Boc solid-phase synthesis, make it essential in both industrial and academic settings.