Fmoc-D-Trp(Boc)-OH
97%
Reagent
Code: #58017
Alias
Fmoc-D-
CAS Number
163619-04-3
blur_circular Chemical Specifications
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Molecular Information
Weight
526.58 g/mol
Formula
C₃₁H₃₀N₂O₆
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Registry Numbers
MDL Number
MFCD00153367
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Storage & Handling
Storage
2~8°C
description Product Description
This compound is widely used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS) methods. It serves as a protected amino acid derivative, where the Fmoc (fluorenylmethyloxycarbonyl) group protects the amine functionality, and the Boc (tert-butyloxycarbonyl) group protects the indole side chain of tryptophan. Its primary application is in the construction of peptide chains, ensuring selective deprotection and coupling steps during synthesis. It is especially valuable in synthesizing peptides containing tryptophan residues, as it prevents unwanted side reactions. The compound is commonly employed in pharmaceutical research, biotechnology, and the development of therapeutic peptides, where precise and controlled peptide assembly is critical. Its stability and compatibility with SPPS protocols make it a reliable choice for producing complex peptides with high purity.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Purity (HPLC) | 97-100% |
| Specific Rotation (A20DC1, DMF) | 16.5-21.5 |
| Appearance | White to light yellow powder |
| Elemental Analysis | Consistent |
| Proton NMR Spectrum | Conforms to Structure |
| TLC Analysis | One spot |
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