Boc-Asp(OtBu)-ONp
≥95%
Reagent
Code: #53389
CAS Number
29365-05-7
blur_circular Chemical Specifications
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Molecular Information
Weight
410.42 g/mol
Formula
C₁₉H₂₆N₂O₈
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Registry Numbers
MDL Number
MFCD00076913
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Storage & Handling
Storage
2-8°C, dry and sealed
description Product Description
Used primarily in peptide synthesis, this compound serves as a protected derivative of aspartic acid. It facilitates the incorporation of aspartic acid into peptide chains while preventing unwanted side reactions. The Boc (tert-butyloxycarbonyl) group protects the amino group, and the OtBu (tert-butyl ester) group safeguards the carboxyl group. The ONp (para-nitrophenyl ester) moiety enhances reactivity, making it easier to form peptide bonds. This reagent is particularly valuable in solid-phase peptide synthesis, where selective deprotection and coupling steps are critical. Its application ensures efficient and controlled assembly of complex peptides, especially in pharmaceutical research and production of bioactive peptides.
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