N-Cbz-N'-trityl-L-asparagine
98%
Reagent
Code: #52248
CAS Number
132388-57-9
blur_circular Chemical Specifications
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Molecular Information
Weight
508.56 g/mol
Formula
C₃₁H₂₈N₂O₅
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Registry Numbers
MDL Number
MFCD00153326
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Physical Properties
Boiling Point
775.979°C at 760 mmHg
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Storage & Handling
Storage
2-8°C, dry and sealed
description Product Description
This chemical is primarily used in peptide synthesis as a protecting group for the amine and side chain functionalities of asparagine. The N-Cbz (carbobenzoxy) group protects the amine, while the N'-trityl (triphenylmethyl) group shields the side chain amide, ensuring selective reactions during peptide bond formation. It is particularly valuable in solid-phase peptide synthesis (SPPS) where precise control over protecting groups is essential to avoid unwanted side reactions. Additionally, it aids in the purification and isolation of peptides by providing stability to the asparagine residue during complex synthetic processes. Its use is critical in the production of biologically active peptides and pharmaceutical compounds.
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