Fmoc-Phe(4-CF3)-OH
≥95%
Reagent
Code: #50395
CAS Number
247113-86-6
blur_circular Chemical Specifications
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Molecular Information
Weight
455.43 g/mol
Formula
C₂₅H₂₀F₃NO₄
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Registry Numbers
MDL Number
MFCD00797581
thermostat
Physical Properties
Melting Point
128-138°C
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Storage & Handling
Storage
2-8°C, dry and sealed
description Product Description
This compound is primarily used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS) methods. It serves as a protected amino acid derivative, where the Fmoc (fluorenylmethyloxycarbonyl) group acts as a temporary protecting group for the amino functionality. The presence of the trifluoromethyl (CF3) group on the phenyl ring enhances the hydrophobicity and stability of the peptide, making it useful in the development of peptides with specific structural or functional properties. It is often employed in the synthesis of modified peptides for research in drug discovery, biochemical studies, and the development of peptide-based therapeutics. The CF3 group can also influence the peptide's interaction with biological targets, making it valuable in designing peptides with enhanced binding affinity or selectivity.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Appearance | White to Faint Beige Powder |
| Purity (%) | 95-100 |
| Infrared Spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
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