(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-methyl-3-phenylpropanoic acid

≥95%

Reagent Code: #50135
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CAS Number 152436-04-9

science Other reagents with same CAS 152436-04-9

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 401.45 g/mol
Formula C₂₅H₂₃NO₄
badge Registry Numbers
MDL Number MFCD02259493
thermostat Physical Properties
Boiling Point 621.2°C at 760 mmHg
inventory_2 Storage & Handling
Storage 2-8°C, dry and sealed

description Product Description

This compound is the Fmoc-protected (R)-α-methyl-L-phenylalanine (Fmoc-(R)-2-methyl-3-phenylpropanoic acid), a specialized building block for solid-phase peptide synthesis (SPPS). The Fmoc group selectively protects the α-amino group, offering stability under basic coupling conditions and facile removal with mild acids (e.g., piperidine), which facilitates efficient, stepwise peptide chain assembly on resin supports. The α-methyl substitution imparts steric hindrance, enhancing proteolytic stability and conformational rigidity in peptides, ideal for peptidomimetics, drug discovery, and bioactive peptide design. Its defined (R)-chirality preserves stereochemical control throughout synthesis.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿2,538.00
inventory 5g
10-20 days ฿23,436.00
inventory 10g
10-20 days ฿39,087.00
inventory 1g
10-20 days ฿6,354.00

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(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-methyl-3-phenylpropanoic acid
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This compound is the Fmoc-protected (R)-α-methyl-L-phenylalanine (Fmoc-(R)-2-methyl-3-phenylpropanoic acid), a specialized building block for solid-phase peptide synthesis (SPPS). The Fmoc group selectively protects the α-amino group, offering stability under basic coupling conditions and facile removal with mild acids (e.g., piperidine), which facilitates efficient, stepwise peptide chain assembly on resin supports. The α-methyl substitution imparts steric hindrance, enhancing proteolytic stability and

This compound is the Fmoc-protected (R)-α-methyl-L-phenylalanine (Fmoc-(R)-2-methyl-3-phenylpropanoic acid), a specialized building block for solid-phase peptide synthesis (SPPS). The Fmoc group selectively protects the α-amino group, offering stability under basic coupling conditions and facile removal with mild acids (e.g., piperidine), which facilitates efficient, stepwise peptide chain assembly on resin supports. The α-methyl substitution imparts steric hindrance, enhancing proteolytic stability and conformational rigidity in peptides, ideal for peptidomimetics, drug discovery, and bioactive peptide design. Its defined (R)-chirality preserves stereochemical control throughout synthesis.

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