Fmoc-Arg(Alloc)2-OH
97%
blur_circular Chemical Specifications
description Product Description
This chemical is primarily used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS) methods. It serves as a protected form of arginine, where the Fmoc (fluorenylmethyloxycarbonyl) group protects the amino group, and the Alloc (allyloxycarbonyl) groups protect the side chain guanidine moiety. This protection strategy allows for selective deprotection during the synthesis process, enabling the stepwise assembly of peptides with high precision. It is especially useful in the synthesis of complex peptides or those containing multiple arginine residues, as it prevents unwanted side reactions and ensures the correct sequence is achieved. After synthesis, the Alloc groups can be removed under mild conditions, typically using palladium catalysts, without affecting other protecting groups in the peptide. This makes it a valuable reagent in the production of bioactive peptides, pharmaceutical compounds, and research peptides.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Appearance | White to off-white Solid |
| Purity (%) | 96.5-100% |
| Optical Rotation (C=1.00 g/100 mL DMF) (°) | -9.6 to -3.6 |
| MS | Conforms to Structure |
| Infrared Spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
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