Z-Arg(Pbf)-OH.CHA is widely used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS). It serves as a protected form of arginine, where the Pbf (2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl) group protects the guanidine side chain, preventing unwanted reactions during peptide chain assembly. This compound is essential for constructing peptides with arginine residues, ensuring high yield and purity. It is commonly employed in the production of therapeutic peptides, research peptides, and biochemical studies. The CHA (cyclohexylamine) salt form enhances its stability and solubility, making it easier to handle in laboratory settings. Its application is critical in fields like drug development, where precise peptide sequences are required for effective and targeted treatments.