3-(2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)ethoxy)propanoic acid

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Reagent Code: #44218
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CAS Number 1654740-73-4

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 355.38 g/mol
Formula C₂₀H₂₁NO₅
badge Registry Numbers
MDL Number MFCD16294357
thermostat Physical Properties
Boiling Point 589.9±40.0°C at 760 mmHg
inventory_2 Storage & Handling
Storage 2-8°C, dry and sealed

description Product Description

This compound is an Fmoc-protected linker molecule, specifically 3-(2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)ethoxy)propanoic acid, used in solid-phase peptide synthesis (SPPS) and bioconjugation applications. It consists of an Fmoc-protected primary amine linked through an ethyleneoxy spacer to a propanoic acid group. The carboxylic acid terminus enables facile coupling to resins, peptides, or other biomolecules, while the Fmoc group safeguards the amine during synthesis and can be selectively removed with piperidine under mild basic conditions. This structure imparts hydrophilicity and flexibility, making it ideal for enhancing peptide solubility, creating PEG-like spacers in peptide-drug conjugates, and modifying proteins or oligonucleotides for improved pharmacokinetics and stability. Its orthogonality with common SPPS reagents ensures high efficiency in multistep assemblies.

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Test Parameter Specification
Appearance White to off-white solid
Purity 96.5-100
Infrared Spectrum Conforms to Structure
NMR Conforms to Structure

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 1g
10-20 days ฿5,560.00
inventory 100mg
10-20 days ฿1,680.00
inventory 250mg
10-20 days ฿3,360.00

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