(S)-3-(3-(((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)methyl)phenyl)-2-((tert-butoxycarbonyl)amino)propanoic acid
95%
Reagent
Code: #232535
CAS Number
959573-13-8
blur_circular Chemical Specifications
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Molecular Information
Weight
516.58 g/mol
Formula
C₃₀H₃₂N₂O₆
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Registry Numbers
MDL Number
MFCD06659131
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Physical Properties
Boiling Point
733.2±60.0 °C(Predicted)
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Storage & Handling
Density
1.245±0.06 g/cm3(Predicted)
Storage
2-8°C, sealed, dry, light-proof
description Product Description
Widely used in peptide synthesis, this compound serves as a chiral building block for the preparation of complex peptides and peptidomimetics. Its structure incorporates orthogonal protecting groups—Fmoc and Boc—that allow selective deprotection under different conditions, enabling stepwise assembly of peptide chains. The Fmoc group is base-labile and commonly removed with piperidine, while the Boc group is acid-labile, removed under mild acidic conditions like trifluoroacetic acid. This dual protection makes it ideal for solid-phase peptide synthesis (SPPS), especially in automated systems. The aromatic fluorenyl group enhances solubility in organic solvents and provides UV detectability, aiding in reaction monitoring and purification. It is particularly valuable in the synthesis of bioactive peptides, pharmaceutical intermediates, and labeled peptides for research.
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