tert-Butyl 2-(benzyloxycarbonylamino)-2-methylpropanoate
95%
Reagent
Code: #150221
CAS Number
4512-31-6
blur_circular Chemical Specifications
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Molecular Information
Weight
293.36 g/mol
Formula
C₁₆H₂₃NO₄
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Registry Numbers
MDL Number
MFCD20040503
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Physical Properties
Boiling Point
405.4±38.0 °C(Predicted)
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Storage & Handling
Density
1.085±0.06 g/cm3(Predicted)
Storage
2-8°C
description Product Description
Used as a protected amino acid derivative in peptide synthesis, particularly in solid-phase and solution-phase methods. The tert-butyl ester group provides acid-labile protection for the carboxylic acid, while the benzyloxycarbonyl (Cbz) group protects the amino functionality and can be removed selectively by hydrogenolysis. Its sterically hindered structure helps reduce racemization during coupling steps, making it valuable for synthesizing complex peptides with high purity. Commonly employed in the preparation of intermediates for pharmaceuticals and bioactive molecules.
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