Boc-Oic-OH
97%
Reagent
Code: #145676
CAS Number
109523-13-9
blur_circular Chemical Specifications
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Molecular Information
Weight
269.34 g/mol
Formula
C₁₄H₂₃NO₄
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Registry Numbers
MDL Number
MFCD09750486
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Physical Properties
Melting Point
134-136°C
Boiling Point
400.9±28.0°C
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Storage & Handling
Storage
2-8°C
description Product Description
Used primarily in peptide synthesis as a protected amino acid derivative, enabling selective coupling reactions without interference from reactive side chains. The Boc (tert-butoxycarbonyl) group acts as a temporary protecting group for the amine functionality, allowing stepwise assembly of complex peptides. After coupling, the Boc group can be easily removed under mild acidic conditions, leaving other protecting groups intact. This makes it valuable in solid-phase and solution-phase peptide synthesis, especially in the production of pharmaceuticals and bioactive peptides. Also utilized in the synthesis of peptidomimetics and as an intermediate in the development of protease inhibitors.
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