Used in peptide synthesis as a protected tyrosine derivative featuring an acetyl group at the 3-position of the aromatic ring, enabling selective coupling reactions in the production of complex peptides and proteins. The benzyloxycarbonyl (Cbz) group protects the amino functionality, the benzyl group protects the hydroxyl site at position 4, and the methyl ester protects the carboxyl group. This multi-protection strategy, combined with the 3-acetyl modification, allows stepwise assembly of peptides with high regio- and stereocontrol. Commonly employed in solid-phase and solution-phase synthesis for pharmaceutical research, including the development of enzyme inhibitors and bioactive peptides.