6-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)hexanoic acid
97%
Reagent
Code: #120390
CAS Number
173690-47-6
blur_circular Chemical Specifications
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Molecular Information
Weight
367.44 g/mol
Formula
C₂₂H₂₅NO₄
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Registry Numbers
MDL Number
MFCD30596881
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Storage & Handling
Storage
2-8°C, dry and sealed
description Product Description
This compound, known as Fmoc-N-methyl-6-aminohexanoic acid, serves as a protected building block in solid-phase peptide synthesis (SPPS). The fluorenylmethyloxycarbonyl (Fmoc) group protects the N-methylamine functionality, enabling selective amide bond formation while preventing side reactions. Fmoc is stable under mildly acidic conditions but can be efficiently removed using mild bases like piperidine, facilitating controlled, stepwise peptide chain elongation. The hexanoic acid moiety acts as a spacer, improving solubility in organic solvents and supporting efficient reactions and purification in peptide assembly.
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