3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-(((benzyloxy)carbonyl)amino)propanoic acid
97%
blur_circular Chemical Specifications
description Product Description
This compound is a protected derivative of 2,3-diaminopropanoic acid (Dap), with the benzyloxycarbonyl (Cbz) group on the α-amino group and the fluorenylmethoxycarbonyl (Fmoc) group on the β-amino group. It serves as a specialized building block in solid-phase peptide synthesis (SPPS), enabling the incorporation of this non-proteinogenic amino acid into peptide sequences. The orthogonal protecting groups prevent side reactions during assembly: Fmoc is removed under basic conditions (e.g., piperidine), while Cbz is cleaved under acidic conditions or by hydrogenation. This selectivity ensures high-yield synthesis of complex peptides for applications in pharmaceutical research, drug development, and biochemical studies.
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