(R)-(9H-Fluoren-9-yl)methyl 2-(hydroxymethyl)pyrrolidine-1-carboxylate
≥95%
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description Product Description
This compound, (R)-(9H-Fluoren-9-yl)methyl 2-(hydroxymethyl)pyrrolidine-1-carboxylate, also known as Fmoc-(R)-prolinol, is a specialty chemical used in organic synthesis, particularly in peptide and peptidomimetic chemistry. It features the fluorenylmethyloxycarbonyl (Fmoc) protecting group on the nitrogen of the pyrrolidine ring derived from (R)-proline, leaving the primary hydroxyl group free for selective functionalization. In solid-phase peptide synthesis (SPPS), it serves as a building block to incorporate a C-terminal alcohol moiety or as a linker, enabling the construction of peptides and bioactive molecules without interference from the amine. The Fmoc group provides stability under basic conditions and facile removal with mild acids, making it essential for stepwise assembly in pharmaceutical and biochemical applications.
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