(R)-(9H-Fluoren-9-yl)methyl 2-(hydroxymethyl)pyrrolidine-1-carboxylate

≥95%

Reagent Code: #113600
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CAS Number 215178-45-3

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 323.39 g/mol
Formula C₂₀H₂₁NO₃
badge Registry Numbers
MDL Number MFCD00270370
thermostat Physical Properties
Boiling Point 504.6±23.0°C at 760 mmHg
inventory_2 Storage & Handling
Storage -20°C, dry sealed

description Product Description

This compound, (R)-(9H-Fluoren-9-yl)methyl 2-(hydroxymethyl)pyrrolidine-1-carboxylate, also known as Fmoc-(R)-prolinol, is a specialty chemical used in organic synthesis, particularly in peptide and peptidomimetic chemistry. It features the fluorenylmethyloxycarbonyl (Fmoc) protecting group on the nitrogen of the pyrrolidine ring derived from (R)-proline, leaving the primary hydroxyl group free for selective functionalization. In solid-phase peptide synthesis (SPPS), it serves as a building block to incorporate a C-terminal alcohol moiety or as a linker, enabling the construction of peptides and bioactive molecules without interference from the amine. The Fmoc group provides stability under basic conditions and facile removal with mild acids, making it essential for stepwise assembly in pharmaceutical and biochemical applications.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿2,835.00
inventory 1g
10-20 days ฿5,643.00

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