4-[(2,4-Dimethoxyphenyl)(Fmoc-amino)methyl]phenoxyacetic acid
98%
Reagent
Code: #105883
Alias
4-[(2,4-Dimethoxyphenyl)(Fmoc-amino)methyl]phenoxyacetic acid;linker
CAS Number
145069-56-3
blur_circular Chemical Specifications
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Molecular Information
Weight
539.58 g/mol
Formula
C₃₂H₂₉NO₇
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Registry Numbers
MDL Number
MFCD00153509
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Physical Properties
Melting Point
~180 °C (dec.)
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Storage & Handling
Storage
2~8°C
description Product Description
This chemical is primarily used in peptide synthesis as a building block for solid-phase peptide synthesis (SPPS). It serves as a protected amino acid derivative, where the Fmoc (fluorenylmethyloxycarbonyl) group acts as a temporary protecting group for the amine functionality. The phenoxyacetic acid moiety enhances its attachment to resin supports, facilitating the stepwise assembly of peptides. Its application is crucial in the development of pharmaceuticals, bioactive peptides, and research involving peptide-based compounds. The dimethoxyphenyl group provides additional stability during the synthesis process, making it a valuable reagent in organic and medicinal chemistry.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Melting Point | 176-186 |
| Purity (HPLC) | 98-100 |
| 300 MHz NMR Spectrum | Conforms To Structure |
| Appearance | White To Off-White Powder Or Solid |
| Clarity of Solution | Clarify |
| TLC Analysis | One Spot |
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