Used in peptide synthesis as a building block, particularly in solid-phase peptide synthesis (SPPS). The Fmoc group protects the amino group during the synthesis process, ensuring selective reactions. The iodine atom on the phenylalanine side chain allows for further functionalization, such as cross-coupling reactions, enabling the introduction of diverse chemical groups. This makes it valuable in the development of modified peptides for research in drug discovery, biochemistry, and material science. Its chiral nature (D-configuration) is also useful in creating peptides with specific stereochemical properties.