Fmoc-Homoarg-OH is widely used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS). It serves as a protected amino acid derivative, where the Fmoc (fluorenylmethyloxycarbonyl) group protects the amine functionality during the coupling reactions. This compound is especially valuable in the synthesis of peptides containing homoarginine, a non-natural amino acid that mimics the structure and function of arginine. Its application is crucial in the development of peptide-based drugs, bioactive peptides, and research tools for studying protein-protein interactions. Additionally, it is utilized in the preparation of peptide libraries for drug discovery and in the study of enzyme-substrate interactions due to its ability to introduce specific structural modifications in peptide chains.