H-GLY-OBZL P-TOSYLATE
98%
blur_circular Chemical Specifications
description Product Description
H-Gly-OBzl p-tosylate is the p-toluenesulfonate salt of glycine benzyl ester, used primarily in peptide synthesis as a C-terminal protected glycine building block. The benzyl ester group protects the carboxylic acid, allowing selective N-terminal coupling reactions to form peptide bonds without interference from the carboxyl group. This prevents unwanted side reactions and enables precise control over amino acid incorporation. It is particularly useful in solution-phase peptide synthesis and other organic synthesis processes where a free amino group on glycine is required. The tosylate counterion improves solubility and stability, while the benzyl protecting group can be readily removed via hydrogenation or acidolysis in subsequent deprotection steps, making it valuable for producing complex peptides and pharmaceuticals.
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