Boc-Asp(OtBu)-OH
95%
Reagent
Code: #105727
Alias
tert-Butoxycarbonyl-L-Aspartic Acid-4-tert-Butyl Ester ; BOC-L-Aspartic Acid-4-tert-Butyl Ester
CAS Number
1676-90-0
blur_circular Chemical Specifications
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Molecular Information
Weight
289.32 g/mol
Formula
C₁₃H₂₃NO₆
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Registry Numbers
MDL Number
MFCD00076912
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Physical Properties
Melting Point
64-67 °C
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Storage & Handling
Storage
2~8°C
description Product Description
This chemical is widely used in peptide synthesis as a building block. It serves as a protected form of aspartic acid, ensuring specific reactions occur at desired sites without interference. The Boc (tert-butyloxycarbonyl) and OtBu (tert-butyl ester) groups protect the amino and carboxyl functionalities, respectively, during the synthesis process. This allows for controlled step-by-step assembly of peptide chains. It is particularly valuable in solid-phase peptide synthesis (SPPS), where selective deprotection and coupling are essential. Its application ensures high purity and efficiency in producing complex peptides for research, pharmaceuticals, and biotechnology.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Melting Point | 60-65 |
| Purity (HPLC) | 94.5-100 |
| Specific Rotation [a]20/d (c = 1% In Methanol) | |
| Specific Rotation [α]20/D (c = 1% in Methanol) | 1.6-2.4 |
| TLC Analysis | One Spot |
| Appearance | White To Off-White Powder |
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