Nα-Z-D-ornithine is primarily used in peptide synthesis as a protected amino acid derivative. Its application is significant in the development of custom peptides for research purposes, particularly in the study of peptide structure and function. The compound is also utilized in the pharmaceutical industry for the synthesis of peptide-based drugs, where precise control over amino acid configuration and protection is crucial. Additionally, it serves as a building block in the creation of peptidomimetics, which are molecules that mimic the biological activity of peptides but have enhanced stability and bioavailability. This makes it valuable in drug discovery and development processes.