Fmoc-Phg-OH
≥98.5%
Reagent
Code: #105174
Alias
Fmoc-L-phenylglycine, N-fluorenylmethoxycarbonyl-L-phenylglycine
CAS Number
102410-65-1
blur_circular Chemical Specifications
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Molecular Information
Weight
373.4 g/mol
Formula
C₂₃H₁₉NO₄
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Registry Numbers
MDL Number
MFCD00155632
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Physical Properties
Melting Point
175-180 °C
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Storage & Handling
Storage
2~8°C
description Product Description
Used extensively in peptide synthesis as a protecting group for amino acids, particularly in solid-phase peptide synthesis (SPPS). The Fmoc group provides stability during the synthesis process and can be selectively removed under mild basic conditions without affecting other functional groups. It is especially valuable in the synthesis of complex peptides and proteins, ensuring high purity and yield. Additionally, it finds applications in the development of pharmaceuticals, where precise peptide sequences are crucial for drug efficacy. Its role in organic chemistry research is also significant, aiding in the study of peptide structures and interactions.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Melting Point | 174-178 |
| Purity (HPLC) | 98-100% |
| Purity (Neutralization Titration) | 98-102% |
| Specific Rotation [A]20/D (C = 1% in DMF) | 78-84 |
| Appearance | White to Light Yellow Powder |
| Infrared Spectrometry | Conforms To Structure |
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