Fmoc-Ser(tBu)-OH
98%
Reagent
Code: #105135
Alias
FMOC-O-tert-butyl-L-serine ; N-(9-fluorenylmethoxycarbonyl)-O-tert-butyl-L-serine
CAS Number
71989-33-8
blur_circular Chemical Specifications
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Molecular Information
Weight
383.44 g/mol
Formula
C₂₂H₂₅NO₅
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Registry Numbers
EC Number
276-260-6
MDL Number
MFCD00037127
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Physical Properties
Melting Point
130.5-135.5 °C(lit.)
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Storage & Handling
Storage
2~8°C
description Product Description
Fmoc-Ser(tBu)-OH is widely used in solid-phase peptide synthesis (SPPS) as a building block for creating peptides. Its Fmoc (9-fluorenylmethoxycarbonyl) group protects the amino group during synthesis, while the tBu (tert-butyl) group shields the hydroxyl group of serine, preventing unwanted side reactions. This compound is particularly valuable in synthesizing complex peptides and proteins, ensuring high purity and yield. It is also employed in the development of peptide-based drugs, biomaterials, and research tools for studying biological processes. Its stability and compatibility with standard SPPS protocols make it a preferred choice in peptide chemistry.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Purity (HPLC) | 98-100 |
| Specific Rotation [α]20/D (C=1% in Ethyl Acetate) | 24.5-26.5 |
| Specific Rotation [α]20/D (C=1% in Ethyl Acetate) | 24.5-26.5° |
| Appearance | White Powder |
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