Fmoc-Gln(Trt)-OH
95%
Reagent
Code: #105122
Alias
Fmoc-N-trityl-L-glutamine ; Fmoc-N-trityl-L-glutamine
CAS Number
132327-80-1
blur_circular Chemical Specifications
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Molecular Information
Weight
610.7 g/mol
Formula
C₃₉H₃₄N₂O₅
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Registry Numbers
MDL Number
MFCD00077056
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Physical Properties
Melting Point
165-172 °C
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Storage & Handling
Storage
2~8°C
description Product Description
Fmoc-Gln(Trt)-OH is widely used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS). It serves as a protected form of glutamine, where the Fmoc (fluorenylmethyloxycarbonyl) group protects the amino group, and the Trt (trityl) group protects the side chain. This protection ensures selective reactions during peptide chain assembly, preventing unwanted side reactions. It is commonly employed in the production of complex peptides and proteins for research, pharmaceuticals, and biotechnology applications. Its stability and compatibility with SPPS protocols make it a valuable building block for synthesizing peptides with high purity and specificity.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Purity (HPLC) | 95-100 |
| Melting Point | 110-168 |
| Water (Karl Fischer) | 0.1 |
| Specific Rotation [α]20/D (C=1 in DMF) | -15.5 to -12.5 |
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