Fmoc-D-Ser-OH is widely used in peptide synthesis as a building block for creating peptides with specific sequences. It is particularly valuable in solid-phase peptide synthesis (SPPS), where the Fmoc (fluorenylmethyloxycarbonyl) group serves as a protective group for the amino acid during the synthesis process. This compound is essential for introducing D-serine, a non-natural amino acid, into peptide chains, enabling the creation of peptides with unique structural and functional properties. Its application is critical in the development of therapeutic peptides, research tools, and bioactive molecules, where precise control over amino acid configuration is required. Additionally, it is utilized in the study of peptide folding, stability, and interactions, contributing to advancements in biochemistry and drug discovery.