Used in peptide synthesis as a protecting group for thiols, ensuring selective reactions during the formation of complex peptide structures. It is particularly valuable in the synthesis of cysteine-containing peptides, where the trityl group shields the thiol functionality, preventing unwanted side reactions. Additionally, it aids in the preparation of penicillamine derivatives, which are important in chelation therapy for treating metal poisoning and certain autoimmune diseases. Its application extends to research in biochemistry and pharmaceutical development, where precise control over molecular interactions is critical.