Boc-N-Me-Glu(Obzl)-OH
98%
Reagent
Code: #104828
CAS Number
200615-91-4
blur_circular Chemical Specifications
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Molecular Information
Weight
351.39 g/mol
Formula
C₁₈H₂₅NO₆
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Registry Numbers
MDL Number
MFCD00038756
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Physical Properties
Boiling Point
501 °C at 760 mmHg
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Storage & Handling
Storage
2-8°C, dry
description Product Description
This chemical is widely used in peptide synthesis as a protected N-methyl-glutamic acid derivative. Its primary application is in the construction of peptides, where it serves as a building block to introduce N-methyl-glutamic acid residues with specific side-chain protections. The Boc (tert-butoxycarbonyl) group protects the N-methyl amino group, while the Obzl (benzyl ester) group protects the carboxyl side chain, ensuring selective reactivity during peptide elongation. It is particularly useful in solid-phase peptide synthesis (SPPS) and solution-phase methods, enabling the synthesis of complex peptides and proteins. Additionally, it finds use in the development of peptide-based drugs, biomaterials, and research tools, where precise control over amino acid incorporation is essential. Its stability and compatibility with various coupling reagents make it a valuable component in organic and medicinal chemistry workflows.
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