Boc-Phe(3-Me)-OH is widely used in peptide synthesis as a protected amino acid derivative. The tert-butyloxycarbonyl (Boc) group serves as a protective group for the amine functionality, allowing selective peptide bond formation without unwanted side reactions. The 3-methyl substitution on the phenylalanine side chain introduces steric and electronic effects, which can be useful in designing peptides with specific structural or functional properties. This compound is particularly valuable in the development of bioactive peptides, where precise control over amino acid incorporation is essential. It is also employed in medicinal chemistry for the synthesis of peptide-based drugs, where the modified phenylalanine can enhance stability, binding affinity, or pharmacokinetic properties. Additionally, it finds applications in research for studying enzyme-substrate interactions and protein folding mechanisms due to its unique structural features.