4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-1-methyl-1H-pyrrole-2-carboxylic acid
98%
Reagent
Code: #104575
CAS Number
195387-29-2
blur_circular Chemical Specifications
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Molecular Information
Weight
362.38 g/mol
Formula
C₂₁H₁₈N₂O₄
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Registry Numbers
MDL Number
MFCD02094546
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Storage & Handling
Storage
Room temperature, airtight, dry
description Product Description
This compound, 4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-1-methyl-1H-pyrrole-2-carboxylic acid, is a specialized Fmoc-protected building block used in solid-phase peptide synthesis (SPPS). The Fmoc group protects the amino group at the 4-position of the 1-methylpyrrole ring, enabling controlled incorporation of the pyrrole-2-carboxylic acid moiety into peptide chains. It prevents unwanted side reactions during coupling steps and can be selectively removed under mild basic conditions, such as with piperidine. This reagent is essential for synthesizing complex peptides containing non-natural pyrrole units, with applications in medicinal chemistry, drug discovery, and biochemical research.
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