Fmoc-N-(tert-butyloxycarbonylmethyl)glycine
95%
science Other reagents with same CAS 141743-16-0
blur_circular Chemical Specifications
description Product Description
This compound, Fmoc-N-(tert-butyloxycarbonylmethyl)glycine, is a protected derivative of N-(carboxymethyl)glycine utilized primarily in solid-phase peptide synthesis (SPPS). The Fmoc (fluorenylmethyloxycarbonyl) group acts as a temporary protecting group for the amino nitrogen, enabling orthogonal deprotection. The tert-butyl ester within the N-(tert-butyloxycarbonylmethyl) substituent protects the additional carboxylic acid group, allowing selective coupling and stepwise peptide assembly. This dual protection strategy is crucial for constructing complex peptides with modified linkages or structures. It finds applications in developing peptide-based drugs, biomaterials, and research tools in biochemistry and molecular biology.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Appearance | White to Off-White Solid |
| Purity (%) | 94.5-100 |
| Infrared spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
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