Fmoc-N-(tert-butyloxycarbonylmethyl)glycine

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Reagent Code: #104444
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CAS Number 141743-16-0

science Other reagents with same CAS 141743-16-0

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 411.45 g/mol
Formula C₂₃H₂₅NO₆
badge Registry Numbers
MDL Number MFCD05663767
inventory_2 Storage & Handling
Storage 2-8°C

description Product Description

This compound, Fmoc-N-(tert-butyloxycarbonylmethyl)glycine, is a protected derivative of N-(carboxymethyl)glycine utilized primarily in solid-phase peptide synthesis (SPPS). The Fmoc (fluorenylmethyloxycarbonyl) group acts as a temporary protecting group for the amino nitrogen, enabling orthogonal deprotection. The tert-butyl ester within the N-(tert-butyloxycarbonylmethyl) substituent protects the additional carboxylic acid group, allowing selective coupling and stepwise peptide assembly. This dual protection strategy is crucial for constructing complex peptides with modified linkages or structures. It finds applications in developing peptide-based drugs, biomaterials, and research tools in biochemistry and molecular biology.

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Test Parameter Specification
Appearance White to Off-White Solid
Purity (%) 94.5-100
Infrared spectrum Conforms to Structure
NMR Conforms to Structure

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Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿1,710.00
inventory 1g
10-20 days ฿5,742.00
inventory 100mg
10-20 days ฿900.00
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Fmoc-N-(tert-butyloxycarbonylmethyl)glycine
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This compound, Fmoc-N-(tert-butyloxycarbonylmethyl)glycine, is a protected derivative of N-(carboxymethyl)glycine utilized primarily in solid-phase peptide synthesis (SPPS). The Fmoc (fluorenylmethyloxycarbonyl) group acts as a temporary protecting group for the amino nitrogen, enabling orthogonal deprotection. The tert-butyl ester within the N-(tert-butyloxycarbonylmethyl) substituent protects the additional carboxylic acid group, allowing selective coupling and stepwise peptide assembly. This dual prot

This compound, Fmoc-N-(tert-butyloxycarbonylmethyl)glycine, is a protected derivative of N-(carboxymethyl)glycine utilized primarily in solid-phase peptide synthesis (SPPS). The Fmoc (fluorenylmethyloxycarbonyl) group acts as a temporary protecting group for the amino nitrogen, enabling orthogonal deprotection. The tert-butyl ester within the N-(tert-butyloxycarbonylmethyl) substituent protects the additional carboxylic acid group, allowing selective coupling and stepwise peptide assembly. This dual protection strategy is crucial for constructing complex peptides with modified linkages or structures. It finds applications in developing peptide-based drugs, biomaterials, and research tools in biochemistry and molecular biology.

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