This chemical is primarily used in peptide synthesis, where it serves as a protected form of histidine. The benzyl (Bzl) group protects the imidazole side chain of histidine during the synthesis process, preventing unwanted reactions. It is particularly valuable in solid-phase peptide synthesis (SPPS) and solution-phase peptide synthesis, enabling the creation of complex peptides with high precision. Additionally, it is utilized in the development of peptide-based pharmaceuticals, where histidine plays a critical role in biological activity, such as in enzyme active sites or metal ion binding. Its application extends to research in biochemistry and medicinal chemistry, where it aids in studying protein structure and function.