Boc-N-Me-Nle-OH is the tert-butoxycarbonyl (Boc)-protected derivative of N-methyl-L-norleucine, serving as a key building block in peptide synthesis. The Boc group protects the α-amino group, which can be selectively deprotected using acid, enabling precise stepwise assembly of peptide chains, particularly in solid-phase peptide synthesis (SPPS). It facilitates the selective modification of peptides by preventing unwanted side reactions and is essential for synthesizing complex peptides and proteins with high purity and yield. In pharmaceutical research, it supports the development of peptide-based therapeutics by allowing fine control over peptide structure and function. Its stability across diverse reaction conditions underscores its value in organic and medicinal chemistry.