Fmoc-Ser(HPO3Bzl)-OH
≥97.0% (HPLC)
Reagent
Code: #104096
Alias
Fmoc-benzyl serine phosphate; N-fluorenylmethoxycarbonyl-O-(benzylphosphoryl)-L-serine
CAS Number
158171-14-3
blur_circular Chemical Specifications
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Molecular Information
Weight
497.43 g/mol
Formula
C₂₅H₂₄NO₈P
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Registry Numbers
MDL Number
MFCD00797869
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Storage & Handling
Storage
2~8°C
description Product Description
This chemical is primarily used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS). It serves as a protected amino acid derivative, where the Fmoc (fluorenylmethyloxycarbonyl) group acts as a temporary protecting group for the amino group, while the HPO3Bzl (benzyl phosphate) group protects the serine side chain. This protection strategy allows for the selective deprotection and coupling of amino acids during the synthesis process. It is especially useful in constructing phosphorylated peptides, which are important in studying protein phosphorylation, a key regulatory mechanism in cellular signaling pathways. The compound ensures precise control over the incorporation of serine residues with phosphate groups, enabling the production of biologically relevant peptides for research and therapeutic applications.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Purity (HPLC) | 97-100 |
| Infrared Spectrometry | Conforms To Structure |
| Proton NMR Spectrum | Conforms To Structure |
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