Capzimin is primarily utilized in biomedical research due to its role as a potent and selective inhibitor of the 20S proteasome, a key component of the ubiquitin-proteasome pathway. This pathway is crucial for protein degradation and regulation within cells, making Capzimin a valuable tool in studying protein homeostasis and cellular processes. Researchers employ Capzimin to investigate the effects of proteasome inhibition on various diseases, particularly cancer, as uncontrolled protein degradation is often linked to tumor growth and survival. Additionally, it is used to explore neurodegenerative disorders, where proteasome dysfunction is implicated in the accumulation of misfolded proteins. Its specificity allows for targeted studies, aiding in the development of potential therapeutic strategies.