Proteasome Inhibitor 1 is widely used in biochemical research to study the ubiquitin-proteasome pathway, which plays a critical role in protein degradation and regulation within cells. It is particularly valuable in cancer research, where it helps investigate the mechanisms of tumor growth and apoptosis by inhibiting proteasome activity, leading to the accumulation of damaged or misfolded proteins and subsequent cell death. This compound is also utilized in studying neurodegenerative diseases, such as Alzheimer's and Parkinson's, where proteasome dysfunction is implicated. Additionally, it serves as a tool in drug discovery to evaluate the efficacy of novel therapeutic agents targeting proteasome inhibition. Its application extends to understanding immune responses, as proteasome activity is crucial for antigen presentation and immune regulation.