Used in research to study the regulation of peptide hormones and neurotransmitters, as neprilysin plays a key role in degrading substances like amyloid-beta, enkephalins, and natriuretic peptides. The Fc tag allows for easier detection and purification in immunoassays and protein interaction studies. Commonly applied in neuroscience and oncology research due to its involvement in Alzheimer’s disease pathways and tumor cell differentiation, particularly in leukemia where CD10 is a marker. Also utilized in drug development to evaluate inhibitors targeting neprilysin activity.