Used in research to study cell adhesion, proteolysis, and signaling pathways involved in cancer progression and tissue remodeling. Binds to integrins and influences tumor cell migration and invasion. Employed as a detection tool in immunoassays due to the Fc tag, enabling easy quantification and purification. Supports development of therapeutic antibodies by serving as an antigen for screening and characterization. Investigated for its role in inflammatory diseases and metastasis, aiding drug discovery and target validation.