N-(Methoxysuccinyl)-Ala-Ala-Pro-Val chloromethyl ketone
≥98% (TLC)
Reagent
Code: #64931
CAS Number
65144-34-5
science Other reagents with same CAS 65144-34-5
blur_circular Chemical Specifications
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Molecular Information
Weight
502.99 g/mol
Formula
C₂₂H₃₅ClN₄O₇
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Registry Numbers
MDL Number
MFCD00077136
thermostat
Physical Properties
Melting Point
159 °C
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Storage & Handling
Storage
−20°C
description Product Description
This compound is primarily used in biochemical research as a selective inhibitor of serine proteases, particularly elastase. It functions by irreversibly binding to the active site of the enzyme, thereby inhibiting its activity. Researchers utilize it to study the role of elastase in various physiological and pathological processes, such as inflammation and tissue remodeling. Additionally, it is employed in the development of therapeutic agents targeting elastase-related diseases, including chronic obstructive pulmonary disease (COPD) and cystic fibrosis. Its application extends to the investigation of protease mechanisms and the design of enzyme inhibitors in drug discovery.
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