MG-115 is primarily used in research settings as a proteasome inhibitor. It plays a key role in studying protein degradation pathways within cells, particularly in the ubiquitin-proteasome system. By inhibiting proteasomal activity, MG-115 helps scientists investigate the accumulation of damaged or misfolded proteins, which is relevant in understanding neurodegenerative diseases such as Alzheimer's and Parkinson's. It is also employed in cancer research to explore how blocking protein breakdown affects tumor cell survival and apoptosis. Due to its ability to induce cell stress and death in certain malignancies, MG-115 serves as a tool compound for evaluating potential therapeutic strategies targeting proteasome function. Its application remains largely confined to laboratory studies and is not used clinically.