1-(4-Boronobenzoyl)piperidine-4-carboxylic acid
98%
Reagent
Code: #154442
CAS Number
850593-02-1
blur_circular Chemical Specifications
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Molecular Information
Weight
277.08 g/mol
Formula
C₁₃H₁₆BNO₅
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Registry Numbers
MDL Number
MFCD07363784
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Physical Properties
Melting Point
110-114 °C
Boiling Point
571.8 °C at 760 mmHg
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Storage & Handling
Storage
2-8°C, sealed, dry
description Product Description
Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of proteasome inhibitors for cancer therapy. Its boronic acid functional group enables reversible binding to enzyme active sites, enhancing selectivity and potency. Commonly employed in targeted protein degradation research and in the preparation of boron-containing drugs that exhibit improved pharmacokinetic profiles. Also utilized in Suzuki-Miyaura cross-coupling reactions for constructing complex bioactive molecules.
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