Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of protease inhibitors and antiviral drugs. Its rigid biphenyl-cyclopropane scaffold enhances binding selectivity and metabolic stability in drug candidates. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies due to its ability to modulate lipophilicity and conformational restraint. Also utilized in the preparation of fluorinated analogs to improve bioavailability and membrane permeability in central nervous system (CNS) targeting compounds.