2-(2,6-dioxopiperidin-3-yl)-5-nitroisoindoline-1,3-dione

95%

Reagent Code: #64522
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CAS Number 55003-81-1

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 303.23 g/mol
Formula C₁₃H₉N₃O₆
inventory_2 Storage & Handling
Storage 2-8℃

description Product Description

This compound is primarily utilized in the field of medicinal chemistry, particularly in the development of targeted cancer therapies. It functions as a key component in the design of proteolysis-targeting chimeras (PROTACs), which are innovative molecules that facilitate the degradation of specific proteins involved in cancer progression. By binding to both the target protein and an E3 ubiquitin ligase, it induces the ubiquitination and subsequent degradation of the target protein, thereby inhibiting cancer cell growth and survival. Additionally, it has been explored for its potential in treating neurodegenerative diseases by targeting misfolded proteins that contribute to disease pathology. Its unique structure allows for precise interaction with biological targets, making it a valuable tool in the development of novel therapeutic agents.

format_list_bulleted Product Specification

Test Parameter Specification
Appearance Off-white solid
Purity 94.5-100
NMR Conforms to Structure

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Size Availability Unit Price Quantity
inventory 25g
10-20 days ฿81,760.00
inventory 5g
10-20 days ฿24,110.00
inventory 1g
10-20 days ฿8,200.00

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