2-chloro-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)acetamide

95%

Reagent Code: #64516
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CAS Number 444287-84-7

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 349.73 g/mol
Formula C₁₅H₁₂ClN₃O₅
inventory_2 Storage & Handling
Storage 2-8℃

description Product Description

This chemical is primarily utilized in the field of medicinal chemistry for the development of targeted therapeutic agents. It serves as a key intermediate in the synthesis of proteolysis-targeting chimeras (PROTACs), which are innovative molecules designed to degrade specific disease-causing proteins within cells. Its structure is particularly valuable in creating compounds that can bind to both the target protein and an E3 ubiquitin ligase, facilitating the ubiquitination and subsequent degradation of the protein. This approach is being actively explored for the treatment of various diseases, including cancer, neurodegenerative disorders, and autoimmune conditions. Additionally, its role in drug discovery extends to optimizing pharmacokinetic properties and enhancing the efficacy of small-molecule drugs.

format_list_bulleted Product Specification

Test Parameter Specification
Appearance Light yellow solid
Purity 94.5-100
NMR Conforms to Structure

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 10g
10-20 days ฿62,940.00
inventory 100mg
10-20 days ฿14,110.00
inventory 1g
10-20 days ฿23,520.00
inventory 250mg
10-20 days ฿17,640.00

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