2-(2,6-Dioxopiperidin-3-yl)-5-hydroxyisoindoline-1,3-dione

95%

Reagent Code: #176984
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CAS Number 64567-60-8

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 274.23 g/mol
Formula C₁₃H₁₀N₂O₅
badge Registry Numbers
MDL Number MFCD24386541
inventory_2 Storage & Handling
Storage Room temperature, inert gas storage

description Product Description

Used primarily in pharmaceutical research as a derivative of thalidomide, this compound serves as a key intermediate in the development of immunomodulatory drugs. It plays a significant role in targeted protein degradation therapies, particularly in the design of cereblon E3 ligase modulators. These modulators are investigated for their ability to treat various cancers, including multiple myeloma and myelodysplastic syndromes, by promoting the degradation of disease-causing proteins. Its hydroxyl group allows for further chemical modifications, enhancing solubility or binding affinity in drug candidates. Due to its biological activity, it is also used in studies exploring anti-inflammatory and anti-angiogenic pathways.

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Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿560.00
inventory 1g
10-20 days ฿1,420.00
inventory 5g
10-20 days ฿6,620.00
inventory 25g
10-20 days ฿31,090.00

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