2-(2,6-Dioxopiperidin-3-yl)-5-fluoroisoindoline-1,3-dione
98%
Reagent
Code: #176182
CAS Number
835616-61-0
blur_circular Chemical Specifications
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Molecular Information
Weight
276.22 g/mol
Formula
C₁₃H₉FN₂O₄
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Registry Numbers
MDL Number
MFCD30188075
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Physical Properties
Boiling Point
521.5±45.0 °C at 760 mmHg
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Storage & Handling
Density
1.570±0.06 g/cm3
Storage
Room temperature, inert atmosphere
description Product Description
Used primarily in the pharmaceutical industry as an intermediate in the synthesis of immunomodulatory drugs, particularly those targeting cancer and inflammatory diseases. It plays a key role in the production of derivatives that modulate the activity of cereblon, a protein involved in cell signaling and protein degradation pathways. This compound supports the development of therapeutics for multiple myeloma and other hematological malignancies due to its ability to enhance the efficacy of targeted protein degradation. Its structure allows for selective modification, making it valuable in creating potent and specific drug candidates.
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