2-(2,6-Dioxopiperidin-3-yl)-5-hydrazinylisoindoline-1,3-dione
98%
Reagent
Code: #167492
CAS Number
497146-95-9
blur_circular Chemical Specifications
scatter_plot
Molecular Information
Weight
288.26 g/mol
Formula
C₁₃H₁₂N₄O₄
inventory_2
Storage & Handling
Storage
2-8°C, light-proof, inert gas
description Product Description
Used primarily in pharmaceutical research, this compound serves as a key intermediate in the synthesis of targeted protein degraders, particularly cereblon E3 ligase modulators. Its hydrazine functionality allows for further chemical modifications, enabling the development of novel PROTACs (proteolysis-targeting chimeras) and other bifunctional molecules designed to degrade disease-causing proteins. It is also explored for its potential in oncology and immunomodulatory therapies due to its structural similarity to thalidomide derivatives. Commonly employed in medicinal chemistry for linker construction in conjugation strategies, it supports the creation of highly specific drug candidates with improved pharmacokinetic profiles.
shopping_cart Available Sizes & Pricing
Cart
No products
Subtotal:
0.00
Total
0.00
THB