2-(2,6-Dioxopiperidin-3-yl)-5-hydrazinylisoindoline-1,3-dione

98%

Reagent Code: #167492
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CAS Number 497146-95-9

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 288.26 g/mol
Formula C₁₃H₁₂N₄O₄
inventory_2 Storage & Handling
Storage 2-8°C, light-proof, inert gas

description Product Description

Used primarily in pharmaceutical research, this compound serves as a key intermediate in the synthesis of targeted protein degraders, particularly cereblon E3 ligase modulators. Its hydrazine functionality allows for further chemical modifications, enabling the development of novel PROTACs (proteolysis-targeting chimeras) and other bifunctional molecules designed to degrade disease-causing proteins. It is also explored for its potential in oncology and immunomodulatory therapies due to its structural similarity to thalidomide derivatives. Commonly employed in medicinal chemistry for linker construction in conjugation strategies, it supports the creation of highly specific drug candidates with improved pharmacokinetic profiles.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 50mg
10-20 days ฿9,700.00
inventory 250mg
10-20 days ฿28,020.00
inventory 100mg
10-20 days ฿16,480.00

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