4-Chloro-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione

98%

Reagent Code: #164954
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CAS Number 244057-36-1

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 292.67 g/mol
Formula C₁₃H₉ClN₂O₄
badge Registry Numbers
MDL Number MFCD30188071
inventory_2 Storage & Handling
Storage 2-8°C, drying away from light

description Product Description

Used primarily as a key intermediate in the synthesis of immunomodulatory drugs, particularly in the production of lenalidomide and related compounds. It plays a critical role in targeted protein degradation therapies, especially in oncology. The compound functions as a precursor to cereblon E3 ligase modulators, which are employed in the treatment of multiple myeloma, myelodysplastic syndromes, and other hematological cancers. Its structure enables selective binding to cereblon, leading to the degradation of disease-causing proteins. Widely utilized in pharmaceutical research and development for designing novel proteolysis-targeting chimeras (PROTACs) and other degradation-based therapeutics.

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Test Parameter Specification
Appearance Gray solid
Purity (%) 97.5-100%
Infrared Spectrum Conforms to Structure
NMR Conforms to Structure

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿410.00
inventory 250mg
10-20 days ฿810.00
inventory 1g
10-20 days ฿1,950.00
inventory 5g
10-20 days ฿6,650.00
inventory 25g
10-20 days ฿23,490.00

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