3-(5-Bromo-6-fluoro-1-oxoisoindolin-2-yl)piperidine-2,6-dione

98%

Reagent Code: #155355
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CAS Number 2409005-96-3

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 341.13 g/mol
Formula C₁₃H₁₀BrFN₂O₃
inventory_2 Storage & Handling
Storage 2~8℃, dry, sealed

description Product Description

Used in pharmaceutical research as a key intermediate for synthesizing targeted protein degraders, particularly cereblon E3 ligase modulators. Its structure enables selective binding to cereblon, making it valuable in developing anticancer agents, especially for hematological malignancies like multiple myeloma. Also explored in the design of PROTACs (proteolysis-targeting chimeras) due to its ability to recruit E3 ubiquitin ligase, facilitating degradation of disease-causing proteins. Shows potential in improving drug specificity and overcoming resistance in oncology therapies.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿4,380.00
inventory 250mg
10-20 days ฿8,900.00
inventory 1g
10-20 days ฿26,700.00

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